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Introduction

There are 7246 new ORF regions found in human genome (hg38) and were annotated under GENOCODE V35 (Comprehensive) They were described into: uORF, uoORF, dORF, doORF, lncRNA and Processed Transcripts

River flow digram showing disribution of different family of Alu vs ORF

Density (counts) vs Alu Overlapping length

Randomization

Have picked 10215 ORF randomly from hg38 genome (GENCODE V35 Comprehensive) .Then we look for the overlapping alu from 10215 randomly picked ORF .T-Test was done on the randomized data and the original data .This process was repeated 10000 times .The minimum pvalue = 4.38 * 10^(-31) .The maximum pvalue = 5.12 * 10^(-15)